THE IMPORTANCE OF NEUROTRANSMITTERS IN MOOD REGULATION.

GABA (gamma-aminobutyric acid) is an inhibitory neurotransmitter that reduces neuronal excitability and induces relaxation. Low levels of GABA are associated with anxiety and mood disorders.

COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide (WHO,2023).

1 in 6 children aged 2-8 years has a mental, behavioral or developmental disorder

Schema Mood Support Developmental Disorder

The GUT-BRAIN CONNECTION. The role of specific tht-BIOTICS in GABA synthesis

The genome of tht strains was sequenced and confirm the presence of genes involved in the two GABA biosynthetic pathways.

 

What are probiotics in the prolactys Adult Mood Support range of tht ?

The most recent definition of probiotics has been established by the International Scientific Association for Probiotics and Prebiotics (ISAPP).

Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host

References

  • Foster JA, McVey Neufeld KA. Gut-brain axis: how the microbiome influences anxiety and depression. Trends Neurosci. 2013; 36: 305-12.
  • Bravo, J.A.; Forsythe, P.; Chew, M.V.; Escaravage, E.; Savignac, H.M.; Dinan, T.G.; Bienenstock, J.; Cryan, J.F. Ingestion of Lactobacillus Strain Regulates Emotional Behavior and Central GABA Receptor Expression in a Mouse via the Vagus Nerve. Proc. Natl. Acad. Sci. USA 2011, 108, 16050–16055.
  • Zhen-Xiong Zhao, Jie Fu, Shu-Rong Ma, Ran Peng, Jin-Bo Yu, Lin Cong, Li-Bin Pan, Zuo-Guang Zhang, Hui Tian, Chun-Tao Che, Yan Wang, Jian-Dong Jiang; Gut-brain axis metabolic pathway regulates antidepressant efficacy of albiflorin; 2018.

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